GLP-1 FAQ & Compliance — GLP1 One St. Louis

Question 1

What is a GLP-1 medication?

Accepted Answer

GLP-1 (glucagon-like peptide-1) receptor agonists are a class of medications originally developed for type 2 diabetes that have been shown to produce significant weight loss. They work by mimicking a natural hormone that regulates appetite, slows stomach emptying, and signals fullness to the brain. FDA-approved brand names include Ozempic®, Wegovy®, and Mounjaro®. Compounded semaglutide and tirzepatide are the active ingredients in these medications, prepared by licensed compounding pharmacies.

Question 2

What is the difference between semaglutide and tirzepatide?

Accepted Answer

Semaglutide (the active ingredient in Ozempic® and Wegovy®) is a GLP-1 receptor agonist. Tirzepatide (the active ingredient in Mounjaro® and Zepbound®) is a dual GIP+GLP-1 receptor agonist — it activates two pathways instead of one, which clinical trials show produces greater average weight loss. Our medical team will recommend the right option based on your health profile, goals, and BMI.

Question 3

How much weight can I expect to lose?

Accepted Answer

Clinical trials show semaglutide produces an average of 15% body weight loss over 68 weeks, while tirzepatide produces up to 22.5% in some studies. Individual results vary based on starting weight, diet, activity level, and adherence to the program. Most patients begin noticing appetite suppression within the first 1–2 weeks.

Question 4

How is GLP-1 therapy administered?

Accepted Answer

Our standard programs use weekly subcutaneous injections — a small, thin needle injected just under the skin, similar to an insulin pen. We also offer needle-free GLP-1 drops for patients who prefer to avoid injections. Your program guide includes detailed administration instructions, and our support team is available to walk you through your first dose.

Question 5

How long does it take to see results?

Accepted Answer

Most patients experience reduced appetite within the first 1–2 weeks. Measurable weight loss typically begins in weeks 2–4 as the dose is gradually increased. Significant results are usually visible by weeks 8–12. GLP-1 therapy is a gradual, sustainable approach — not a crash diet.

Question 6

What are the most common side effects?

Accepted Answer

The most common side effects are gastrointestinal: nausea, vomiting, diarrhea, and constipation. These are typically mild to moderate and most common when starting or increasing your dose. They usually improve within a few weeks as your body adjusts. Starting at a low dose and gradually increasing — as our programs are designed to do — significantly reduces the likelihood and severity of side effects.

Question 7

Are there serious risks I should know about?

Accepted Answer

GLP-1 medications carry a boxed warning for thyroid C-cell tumors based on animal studies, though this has not been confirmed in humans. They are contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Other rare but serious risks include pancreatitis, gallbladder disease, and kidney injury (usually related to dehydration from nausea/vomiting). Our qualification process screens for these contraindications.

Question 8

Who should NOT use GLP-1 medications?

Accepted Answer

GLP-1 therapy is not appropriate for everyone. You should not use these medications if you have: a personal or family history of medullary thyroid carcinoma or MEN 2; a history of pancreatitis; are pregnant or planning to become pregnant; are breastfeeding; have severe gastrointestinal disease; or have a known allergy to semaglutide or tirzepatide. Our qualification quiz and medical review screen for these conditions before any program is approved.

Question 9

Can I take GLP-1 medications with my other prescriptions?

Accepted Answer

GLP-1 medications can interact with other drugs, particularly oral medications that require consistent absorption timing (such as oral contraceptives and certain diabetes medications). It is essential that you disclose all current medications during your qualification process. Our medical team reviews your full medication list before approving your program.

Question 10

What happens if I stop taking GLP-1 medication?

Accepted Answer

Research shows that most patients regain a significant portion of lost weight after discontinuing GLP-1 therapy, as the medication's appetite-suppressing effects are no longer active. This is why we emphasize using the program as a tool to build sustainable habits — not as a permanent solution on its own. Our 6-month program is designed to give you enough time to establish lasting dietary and lifestyle changes.

Question 11

Is compounded semaglutide legal?

Accepted Answer

Yes. Under Section 503A and 503B of the Federal Food, Drug, and Cosmetic Act, licensed compounding pharmacies may legally prepare compounded versions of FDA-approved drugs, including semaglutide and tirzepatide, when certain conditions are met. GLP1 One works exclusively with state-licensed, 503A-compliant compounding pharmacies. All prescriptions are issued by Missouri-licensed medical providers following a legitimate patient-provider relationship.

Question 12

Do I need a prescription?

Accepted Answer

Yes. GLP-1 medications are prescription-only drugs in the United States. GLP1 One's qualification process establishes a legitimate patient-provider relationship with our Missouri-licensed medical team, who review your health information and issue a prescription if you qualify. We do not dispense medications without a valid prescription from a licensed provider.

Question 13

How does GLP1 One comply with Missouri medical regulations?

Accepted Answer

All prescriptions are issued by providers licensed to practice medicine in Missouri. Our program operates in compliance with Missouri Board of Healing Arts regulations governing telehealth and prescribing practices. Patient records are maintained in accordance with HIPAA and Missouri state privacy laws.

Question 14

Is my health information protected?

Accepted Answer

Yes. GLP1 One is fully HIPAA-compliant. Your health information is encrypted in transit and at rest, never sold to third parties, and used only for the purpose of providing your medical program. You may request a copy of your records or request deletion at any time by contacting us at brian@glp1one.com.

Question 15

What is your refund policy?

Accepted Answer

Due to the nature of compounded prescription medications, we are unable to accept returns of dispensed medications. If you have not yet received your medication and wish to cancel, please contact us within 24 hours of your order. For billing disputes or concerns, contact us at brian@glp1one.com or call 314-314-0188.

Question 16

What does the program cost?

Accepted Answer

Our 30-day starter program begins at $99/month. Our 6-month program offers the best value and is designed for patients committed to meaningful, lasting weight loss. Pricing includes your compounded medication, program guide, and access to our support team. There are no hidden fees — the price you see is the price you pay.

Question 17

Does insurance cover GLP-1 therapy?

Accepted Answer

Most insurance plans do not cover compounded GLP-1 medications. Brand-name GLP-1 drugs (Ozempic, Wegovy, Mounjaro) may be covered for qualifying diagnoses, but coverage varies widely and prior authorization is often required. Our compounded programs are priced to be significantly more affordable than brand-name alternatives — typically 60–80% less.

Question 18

How do I pay?

Accepted Answer

After completing your qualification quiz and receiving approval, you'll receive a secure GoDaddy pay link via email. Payment is processed securely through GoDaddy Payments. We accept all major credit and debit cards.

Question 19

What is included in my program?

Accepted Answer

Your program includes: compounded semaglutide or tirzepatide medication (dosed per your provider's prescription), a detailed program guide with dosing instructions and administration tips, dietary and lifestyle recommendations, and access to our Missouri-based support team for questions throughout your program.

Question 20

Can I upgrade from a 30-day to a 6-month program?

Accepted Answer

Yes. Many patients start with the 30-day program to experience the medication before committing to a longer term. If you'd like to upgrade, contact us at brian@glp1one.com or call 314-314-0188 and we'll apply a credit toward your 6-month program.

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